Physical exercise protects the brain, can prevent dementia. A new study explains how
This is because the synapse, or neural junction, is the site where cognition occurs. According to Britannica, cognition includes all conscious and unconscious processes by which knowledge is accumulated, such as perception, recognition, conception and reasoning.
Casaletto said physical activity, which is a readily available tool, can help stimulate this synaptic functioning.
More Protein Leads to Better Nerve Signals
Older people who remained active had higher levels of proteins that facilitate the exchange of information between neurons, the study found. These results are in line with a previous study by Honer, which found that people who had more of these proteins in their brains when they died were better able to maintain cognition later in life, according to the study.
The researchers found that the effects extended beyond the hippocampus, the brain’s memory seat. As a result, the effects encompass other regions of the brain associated with cognitive function, according to the study.
Honer said it’s possible that physical activity has an overall maintenance effect, supporting and boosting healthy protein function. These proteins facilitate synaptic transmission throughout the brain, he said.
Synapses protect brains showing signs of dementia
Amyloid and tau are toxic proteins that characterize the pathology of Alzheimer’s disease. These are accumulated in the brains of most older people.
According to scientists, synapses and neutrons collapse because amyloid accumulates first, followed by tau.
Synaptic integrity, whether measured in the cerebrospinal fluid of living adults or in the brain tissue of autopsied adults, appears to mediate the relationship between amyloid and tau, and between tau and neurodegeneration, according to a previous study conducted. by Casaletto.
She said the neurotoxicity cascade that leads to Alzheimer’s disease appears to be attenuated in older people with higher levels of proteins associated with synaptic integrity.
She said both studies show the potential importance of maintaining synaptic health in supporting the brain against Alzheimer’s disease.